A new study came out at the beginning of the month (Aug 2015) that looked at endocrine disruption effect of Roundup in adrenal gland of male rats. Here are two articles( an article and another article) on the study that includes good analysis.
It's an interesting study, and one that may be evidence for someone with adrenal fatigue (or perhaps everyone!) to be certain they are eating only organic food. The study found that the "chronic low dose of Roundup had effects similar to 'adrenal insufficiency in humans'." Even a dose of 10mg/kg bodyweight per day reduced levels of corticosterone (produced in the adrenal glands). Interestingly, no other effects on the rats were seen at this level, of the things they were observing. Why is this number important? The NOAEL (no observed adverse effect level) for chronic toxicity in multiple generation studies was 30mg/kg for adults and 10 mg/kg for offspring.....the level which was found to cause adrenal effects. But get this, the government doesn't include multiple generation studies for endocrine disruption in their regulations.
"Implications of the study
The recent information regarding Roundup® and its metabolites detection in food, water and in human urine [1] signifies the relevance of toxicological studies as one presented. The findings that Roundup® treatment down regulates endogenous ACTH, is similar to the condition known as adrenal insufficiency in humans. This condition manifests as fatigue, anorexia, sweating, anxiety, shaking, nausea, heart palpitations and weight loss. Chronic adrenal insufficiency could be fatal, if untreated. A progressive increase in its prevalence has been observed in humans [8], while a very few studies relating to xenobiotic exposure and adrenal insufficiency development have been reported. The present study describes one of the possible mechanisms of adrenal insufficiency due to Roundup® and suggests more systematic studies, to investigate the area further."
Thinking about how these multi generational studies are set up, what does this say about children of adults who have been eating food with Roundup residue? Would they be more sensitive to the current Roundup in the food supply? What about infants who are drinking soy formula? These are real issues. As more research comes out, the regulatory review boards need to be willing to accept that perhaps these chemicals aren't all they were sold to be. Perhaps, there are very real consequences to health across the board. This study is further evidence that the glyphosate residue in our food supply could indeed be causing underlying conditions in a great many people, even though they appear to be "otherwise healthy".
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